Population pharmacokinetics of olprinone in healthy male volunteers
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چکیده
منابع مشابه
Population pharmacokinetics of olprinone in healthy male volunteers
BACKGROUND Olprinone decreases the cardiac preload and/or afterload because of its vasodilatory effect and increases myocardial contractility by inhibiting phosphodiesterase III. PURPOSE The objective of this study was to characterize the population pharmacokinetics of olprinone after a single continuous infusion in healthy male volunteers. METHODS We used 500 plasma concentration data poin...
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ژورنال
عنوان ژورنال: Clinical Pharmacology: Advances and Applications
سال: 2014
ISSN: 1179-1438
DOI: 10.2147/cpaa.s50626